Ontology, database and tools for nanomaterial safety evaluation

Friederike Ehrhart1, L Rieswijk1, CT Evelo1, H Sarimveis2, P Doganis2, G Drakakis2, B Fadeel3, B Hardy4, J Hastings5, C Helma6, N Jeliazkova7, V Jeliazkov7, P Kohonen8,9, R Grafström9, P Sopasakis10, G Tsiliki2, E Willighagen1

1Department of Bioinformatics - BiGCaT, Maastricht University, 2National Technical University of Athens, 3Karolinska Institutet, 4Douglas Connect, 5European Molecular Biology Laboratory – European Bioinformatics Institute, 6In silico toxicology, 7Ideaconsult Ltd., 8VTT Technical Research Centre of Finland, 9Misvik Biology, 10IMT Institute for Advanced Studies


Poster presented at the Benelux Bioinformatics Conference 2015 eNanoMapper - Ontology, database and tools for nanomaterial safety evaluation Nanomaterials are defined by size: between 1 and 100 nm in at least one dimension. The properties of these material do not always resemble those of the bulk material, i.e. micro- and bigger particles, or solutions. Nanomaterials differ in reactivity, toxicity in biological organisms and ecosystems depending on their size and surface properties and the possibility for “leakage” of the material it is made off. It is difficult to assess the safety of nanomaterials and therefore the NanoSafety Cluster defined a need for a new computational infrastructure in 2012. eNanoMapper is a European project with partners from eight European countries. This project developed a semantic web assisted database, a modular ontology, and tools to use them for nanomaterial safety assessment. Data sharing, data storage, data analysis tools, and web services are currently being developed, tested, and put into production use.

(for full presentation, please visit this link)