A substance database

The first eNanoMapper prototype: a substance database to support safe-by-design

We demonstrate the approach of adopting an ontology-supported data model, describing the materials and measurements. The data sources supported include diverse formats (ISA-Tab, OECD Harmonized Templates, custom spreadsheet templates, various databases provided by consortia members). Besides retaining the data provenance, the focus on measurements provides insights into how to reuse the chemical structure database tools for nanomaterials characterization and safety.

Database for NSI

eNanoMapper database for nanomaterial safety information

We demonstrate how the eNanoMapper database is used to import and publish online ENM and assay data from several data sources, how the “representational state transfer” (REST) API enables building user friendly interfaces and graphical summaries of the data, and how these resources facilitate the modelling of reproducible quantitative structure–activity relationships for nanomaterials (NanoQSAR).


Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-Hand

Toxicological research faces the challenge of integrating knowledge from diverse fields and novel technological devel- opments generally in the biological and medical sciences. We discuss herein the fact that the multiple facets of cancer research, including discovery related to mechanisms, treatment and diagnosis, overlap many up and coming interest areas in toxicology, including the need for improved methods and analysis tools.